Chemistry Services
Bioneeds has state-of-the-art Chemistry labs well supported by experienced scientific team. At Bioneeds we understand our client requirements and offer wide range of chemistry services to support discovery research (medicinal chemistry and agrochemical research) synthetic, analytical and process research (API’s) services.
- Medicinal Chemistry
- Agrochemical Research
- Chiral synthesis & resolution
- Custom synthesis
- Process R&D and CGMP manufacturing
- Analytical chemistry
Medicinal Chemistry Services
- Generation of hits
- Transforming hits to leads
- Optimization of leads
- Developing drug candidates
- Biological screenings against known or client's targets
Agrochemical Research Services
- Helps in discovering novel field candidates
- Hit identification
- Hit to lead
- Lead optimisation
Synthetic Capabilities
- Sensitive reactions from milligram to kilogram scale
- Reaction temperature ranging from from -780C to 2500C
- Chiral chemistry, asymmetric synthesis & chiral resolution
- Halogenation, Nitration, Sulfonation, Cyanation
- LDA, n-Butyllithium, tert-Butyllithium, NaH, NaNH reactions
- NaBH4, LiAlH4, Borane, DIBAL, Pd/C, Pt2O reactions
- Suzuki, Buchwald, Mitsunobu, Friedel-Crafts, Wittig, Grignard reactions
Custom Synthesis
- Bioneeds can offer Custom Synthesis of a wide variety of organic compounds on the milligram to kilogram scale at a competitive price.
- New chemical entities (NCE's)
- Heterocyclic building blocks & scaffolds
- Complex molecules, intermediates & prodrugs
- Reference compounds synthesis
- Metabolites & impurities synthesis
Process Research and Development (R&D) Services
- Route scouting
- Process optimisation
- Impurity profiling
- Identification of critical process parameters using Design of Experiment (DoE)
- Analytical method development
- Process development for ready commercialisation
- Manufacturing from gram to multi kilograms level
Analytical Services
- Raw material characterization as per latest pharmacopoeia (USP / BP / EP / IP / JP)
- Method development as per ICH guidelines
- Method validation as per ICH guidelines
- Impurity profiling, isolation & characterisation
- Trace / heavy metal analysis using AAS and ICP-MS techniques
- Organic Volatile Impurities, Residuals, solvents as per USP
- Extractable & leachable analysis
Bioneeds can offer a number of flexible business models that help you to manage your development risk, conserve your R&D budget, and appropriately reward successful development outcomes.